TFS1 Antibody

Code CSB-PA320357XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TFS1 Polyclonal antibody
Uniprot No.
Target Names
TFS1
Alternative Names
TFS1 antibody; DKA1 antibody; NSP1 antibody; YLR178C antibody; L9470.19Carboxypeptidase Y inhibitor antibody; CPY inhibitor antibody; CDC25 suppressor 1 antibody; I(C) antibody; Ic antibody; Protein DKA1 antibody; Protein NSP1 antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) TFS1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Specific and potent inhibitor of carboxypeptidase Y.
Gene References into Functions
  1. Tfs1p may act as a bridge between cell signaling and intermediate metabolism in yeast. PMID: 22515269
  2. The binding of I(C) to phospholipid membranes was first shown using a liposome-binding assay and by surface plasmon resonance , which revealed that the affinity of this inhibitor was not for phosphatidylethanolamine but for anionic phospholipids. PMID: 17076703
  3. show that the accessibility of the surface pocket of Tfs1p, its N-terminal region and the specific electrostatic properties of a large surface region containing these two elements, play a crucial role in interaction with Ira2 PMID: 17945254
  4. The results obtained demonstrate that the inhibition of Ira2p by Tfs1p is the predominant function under the conditions tested. PMID: 19552705
Subcellular Location
Cytoplasm.
Protein Families
Phosphatidylethanolamine-binding protein family
Database Links

KEGG: sce:YLR178C

STRING: 4932.YLR178C

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