crn Antibody

Code CSB-PA323551XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) crn Polyclonal antibody
Uniprot No.
Target Names
crn
Alternative Names
crn antibody; CG3193Protein crooked neck antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) crn protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May be involved in pre-mRNA splicing process. Involved in embryonic neurogenesis and cell rearrangement during Malpighian tubule morphogenesis.
Gene References into Functions
  1. Through an RNAi-based candidate gene screen, the study identifies the spliceosome factor Crooked neck (Crn) as a regulator of Su(fu) level. PMID: 24603360
  2. Data show that Crn does not have a cell cycle function in the embryo, but is found in a 900 kDa complex together with snRNPs, suggesting that Crn participates in the assembly of the splicing machinery in vivo. PMID: 12163015
Subcellular Location
Nucleus speckle. Note=Concentrated in nuclear speckles.
Protein Families
Crooked-neck family
Tissue Specificity
Transcribed in all cells during embryonic development.
Database Links

KEGG: dme:Dmel_CG3193

STRING: 7227.FBpp0070402

UniGene: Dm.3140

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