csk-1 Antibody

Code CSB-PA941940XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans csk-1 Polyclonal antibody
Uniprot No.
Target Names
csk-1
Alternative Names
csk-1 antibody; Y48G1C.2Tyrosine-protein kinase csk-1 antibody; EC 2.7.10.2 antibody; C-terminal src kinase antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans csk-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Non-receptor tyrosine-protein kinase which plays a role in pharynx function by regulating pumping and the orientation of pharyngeal muscle fibers, independently of src-1 and src-2. May phosphorylate and thereby negatively regulate src-1 and src-2 activities.
Gene References into Functions
  1. results suggest that SRC-1 and KIN-22 play distinct roles under the control of CSK-1 PMID: 12527374
  2. These results suggest that CSK-1 has an essential function in organization of pharyngeal muscle filaments that does not require C. elegans Src family tyrosine kinases. PMID: 19210548
Protein Families
Protein kinase superfamily, Tyr protein kinase family, CSK subfamily
Tissue Specificity
Expressed predominantly in pharyngeal muscles in procorpus, metacorpus and terminal bulb. Expressed also in some neurons (ASE, ADF, AVA, AUA, RMDV and BAG) in the head region, anchor cell, vulva, cells around anus, body wall muscle and gondal distal tip c
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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