CSN1 Antibody

Code CSB-PA009858XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CSN1 Polyclonal antibody
Uniprot No.
Target Names
CSN1
Alternative Names
CSN1 antibody; COP11 antibody; FUS6 antibody; At3g61140 antibody; T20K12.40COP9 signalosome complex subunit 1 antibody; CSN complex subunit 1 antibody; Constitutive photomorphogenesis protein 11 antibody; Protein FUSCA 6 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CSN1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes. The complex is also required for degradation of IAA6 by regulating the activity of the Ubl ligase SCF-TIR complex. In the complex, it plays a central role in CSN assembly.
Gene References into Functions
  1. TSA1 interacts with CSN1 and is involved in Arabidopsis seedling development in darkness. PMID: 22133685
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
CSN1 family
Tissue Specificity
Expressed in leaves, flowers, immature siliques, and light-grown roots.
Database Links

KEGG: ath:AT3G61140

STRING: 3702.AT3G61140.1

UniGene: At.303

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