CSN5 Antibody

Datasheet
Code CSB-PA750847XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q6PC30
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) CSN5 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-) cops5 zgc:73130
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names cops5
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity. In the complex, it probably acts as the catalytic center that mediates the cleavage of nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex.
Subcellular Location Cytoplasm, cytosol, Nucleus, Cytoplasm, perinuclear region, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle
Protein Families Peptidase M67A family, CSN5 subfamily
Database Links

KEGG: dre:393698

STRING: 7955.ENSDARP00000074782

UniGene: Dr.81074

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