Catsup Antibody

Code CSB-PA893699XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Catsup Polyclonal antibody
Uniprot No.
Target Names
Catsup
Alternative Names
Catsup; CG10449; Protein catecholamines up
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Catsup protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Negatively regulates tyrosine hydroxylase activity.
Gene References into Functions
  1. Loss of Catsup function causes Notch to accumulate abnormally in the endoplasmic reticulum (ER) and Golgi compartments, resulting in impaired Notch signaling. In addition, Catsup mutant cells exhibit elevated ER stress, suggesting that impaired zinc homeostasis causes increased levels of misfolded proteins within the secretory compartment. PMID: 23785054
  2. The results of this study concluded that Catsup regulates and links the dopamine synthesis and transport networks. PMID: 21985068
  3. Catsup is a pleiotropic quantitative trait gene, but individual quantitative trait nucleotides do not have pleiotropic effects. Molecular population genetic analyses are consistent with balancing selection maintaining multiple functional polymorphisms. PMID: 16682353
  4. Molecular polymorphisms in Catsup (Catecholamines up) are associated with variation in sleep. PMID: 19234472
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
ZIP transporter (TC 2.A.5) family, KE4/Catsup subfamily
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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