cya Antibody

Code CSB-PA994876XA01BQE
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Product Details

Full Product Name
Rabbit anti-Bacillus anthracis cya Polyclonal antibody
Uniprot No.
Target Names
cya
Alternative Names
cya antibody; pXO1-122 antibody; BXA0141 antibody; GBAA_pXO1_0142Calmodulin-sensitive adenylate cyclase antibody; EC 4.6.1.1 antibody; ATP pyrophosphate-lyase antibody; Adenylyl cyclase antibody; Anthrax edema toxin adenylate cyclase component antibody; Edema factor antibody; EF antibody
Raised in
Rabbit
Species Reactivity
Bacillus anthracis
Immunogen
Recombinant Bacillus anthracis cya protein
Immunogen Species
Bacillus anthracis
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Edema factor (EF), which constitutes one of the three proteins composing the anthrax toxin, causes edema in the host. Acts as a calmodulin-dependent adenylyl cyclase by converting ATP to cAMP, leading to dramatic elevation of intracellular cAMP levels in the host, thereby causing edema. EF is not toxic by itself and only acts as a edema factor when associated with protective antigen (PA) to form the edema toxin (EdTx). Required for the survival of germinated spores within macrophages at the early stages of infection.
Subcellular Location
Secreted. Host cytoplasm, host cytosol.
Protein Families
Adenylyl cyclase class-2 family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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