CYSC1 Antibody

Code CSB-PA256666XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CYSC1 Polyclonal antibody
Uniprot No.
Target Names
CYSC1
Alternative Names
CYSC1 antibody; OAS5 antibody; At3g61440 antibody; F2A19.40Bifunctional L-3-cyanoalanine synthase/cysteine synthase C1 antibody; mitochondrial antibody; EC 2.5.1.47 antibody; EC 4.4.1.9 antibody; Beta-substituted Ala synthase 3;1 antibody; ARAth-Bsas3;1 antibody; Cysteine synthase C1 antibody; AtCYSC1 antibody; O-acetylserine antibody; thiol)-lyase 5 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CYSC1 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a major beta-cyanoalanine synthase. The cyanoalanine synthesis reaction is more efficient than the cysteine synthase activity. Probably unable to interact with SAT and to form the decameric Cys synthase complex (CSC) and is therefore not an enzymatically true OASTL protein. Probably involved in the detoxification of cyanide that arises from ethylene biosynthesis. Maintains a low level of cyanide for proper root hair development.
Gene References into Functions
  1. Genetic crosses between the cas-c1 mutant and scn1 or rhd2 mutants were performed, and the detailed phenotypic and molecular characterization of the double mutants demonstrates that scn1 mutation is epistatic to cas-c1 and cas-c1 is epistatic to rhd2 mutation, indicating that CAS-C1 acts in early steps of the root hair development process.[CAS-C1] PMID: 29490083
  2. essential for maintaining non-toxic concentrations of cyanide in mitochondria to facilitate cyanide's role in signaling PMID: 24398435
  3. the regulation of CYSC1 gene in the plant immune response to pathogen attack PMID: 23784464
  4. The cys-c1 knockout mutant has altered root hair development. PMID: 20935247
Subcellular Location
Mitochondrion.
Protein Families
Cysteine synthase/cystathionine beta-synthase family
Tissue Specificity
Mainly expressed in mature rosette leaves. Also detected in roots, young rosette leaves, stems, cauline leaves, and flowers.
Database Links

KEGG: ath:AT3G61440

STRING: 3702.AT3G61440.1

UniGene: At.21833

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