DACT2 Antibody

Code CSB-PA721117XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q673G8
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) DACT2 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Dapper homolog 2 (Frodo 2) dact2 dpr2 frd2 zgc:152832
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names dact2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Positive regulator of the Wnt signaling pathway which acts downstream of wnt1 indicative for non-canonical Wnt signaling. Also negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors. Required for convergent extension movements in gastrulation.
Subcellular Location Cytoplasm, Late endosome, Nucleus, Cell membrane
Protein Families Dapper family
Database Links

STRING: 7955.ENSDARP00000078756

UniGene: Dr.80140

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