daf-1 Antibody

Code CSB-PA324089XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans daf-1 Polyclonal antibody
Uniprot No.
Target Names
daf-1
Alternative Names
daf-1 antibody; F29C4.1Cell surface receptor daf-1 antibody; EC 2.7.11.30 antibody; Abnormal dauer formation protein 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans daf-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probably involved in a TGF-beta pathway. May be a receptor for TGF-beta-like ligand daf-7. Controls the decision of whether or not larvae enter a developmentally arrested state, known as dauer, in response to environmental conditions. Involved in regulating entry into quiescence triggered by satiety. Involved in sensitivity to CO2 levels. In AWC neurons, acts to promote expression of srsx-3, a member of the GPCR family.
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily
Tissue Specificity
Head and ventral nerve cord from embryos to adults. Expressed in many sensory neurons. Subset of head neurons show coexpression with daf-4 when dauer/nondauer decision is made. Also expressed in non-neuronal cells: membraneous sheath surrounding the dista
Database Links

KEGG: cel:CELE_F29C4.1

STRING: 6239.F29C4.1a

UniGene: Cel.5220

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