dcap-2 Antibody

Datasheet

Code	CSB-PA006557XA01CXY
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Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans dcap-2 Polyclonal antibody

Uniprot No.

O62255

Target Names

dcap-2

Alternative Names

dcap-2 antibody; ndx-5 antibody; F52G2.1mRNA-decapping enzyme 2 antibody; EC 3.6.1.- antibody; Nudix hydrolase 5 antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans dcap-2 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. RNA-decapping enzyme although it does not bind the RNA cap. May contribute to gene regulation in multiple RNA pathways including monomethylguanosine- and trimethylguanosine-capped RNAs. In oocytes, may play a role in the response to stress induced by heat shock, osmotic stress and anoxia. Required for the developmental axon guidance and regrowth of PLM touch receptor neurons. Early in embryogenesis, plays a role in ciliary shape formation in sensory neurons. Promotes survival at high temperatures.

Gene References into Functions

Dcp2 activity can be influenced by both sequence and context, and Dcp2 may contribute to gene regulation in multiple RNA pathways, including monomethyl- and trimethylguanosine-capped RNAs PMID: 16199859

Subcellular Location

Cytoplasmic granule. Cytoplasm, perinuclear region.

Protein Families

Nudix hydrolase family, DCP2 subfamily

Tissue Specificity

Expressed in sensory neurons.

Database Links

KEGG: cel:CELE_F52G2.1

STRING: 6239.F52G2.1b

UniGene: Cel.11986

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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dcap-2 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background