DCR1B Antibody

Datasheet
Code CSB-PA544703XA01DIL
Product Type Polyclonal Antibody
Uniprot No. B0V2S2
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) DCR1B protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias 5' exonuclease Apollo (EC 3.1.-.-) (DNA cross-link repair 1B protein) (SNM1 homolog B) dclre1b snm1b si:dkey-73i4.1 zgc:154089
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names dclre1b
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by terf2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity
Subcellular Location Chromosome, telomere, Nucleus
Protein Families DNA repair metallo-beta-lactamase (DRMBL) family
Database Links

KEGG: dre:768137

STRING: 7955.ENSDARP00000090466

UniGene: Dr.86618

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