dhs-16 Antibody

Datasheet

Code	CSB-PA559807XA01CXY
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Caenorhabditis elegans dhs-16 Polyclonal antibody

Uniprot No.

O16881

Target Names

dhs-16

Alternative Names

dhs-16 antibody; C10F3.23 beta-hydroxysteroid dehydrogenase dhs-16 antibody; EC 1.1.1.- antibody

Raised in

Rabbit

Species Reactivity

Caenorhabditis elegans

Immunogen

Recombinant Caenorhabditis elegans dhs-16 protein

Immunogen Species

Caenorhabditis elegans

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

3beta-hydroxysteroid dehydrogenase that converts 3beta-hydroxysteroids to 3-ketosteroids, an essential step in the production of dafachronic acids from cholesterol. Catalyzes the dehydrogenation of lathosterol (5alpha-cholest-7-en-3beta-ol) to lathosterone (5alpha-cholest-7-en-3-one), a step required for maximal biosynthesis of Delta(7)-dafachronic acid. Dafachronic acids act as ligands and bind directly to the nuclear hormone receptor (NHR) daf-12, suppressing dauer formation and inducing reproductive growth, they can also regulate C.elegans lifespan.

Gene References into Functions

DHS-16 controls DAF-12 activity governing longevity in response to signals from the gonad. PMID: 22505847

Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

Short-chain dehydrogenases/reductases (SDR) family

Tissue Specificity

Strongly expressed in the hypodermis and posterior pharyngeal bulb and in a number of unidentified neurons of the head and tail.

Database Links

KEGG: cel:CELE_C10F3.2

STRING: 6239.C10F3.2

UniGene: Cel.35961

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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