Dhx15 Antibody

Code CSB-PA006870XA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Dhx15 Polyclonal antibody
Uniprot No.
Target Names
Dhx15
Alternative Names
Dhx15 antibody; Ddx15 antibody; Deah9Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 antibody; EC 3.6.4.13 antibody; DEAH box protein 15 antibody
Raised in
Rabbit
Species Reactivity
Mus musculus (Mouse)
Immunogen
Recombinant Mus musculus (Mouse) Dhx15 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.
Gene References into Functions
  1. These data demonstrate that Nlrp6 functions with Dhx15 as a viral RNA sensor to induce IFN-stimulated genes, and this effect is especially important in the intestinal tract. PMID: 26494172
  2. DHX15, a DEXDc helicase family member, plays an important role in sensing RNA and RNA viruses in bone marrow dendritic cells. PMID: 24990078
Subcellular Location
Nucleus. Nucleus, nucleolus.
Protein Families
DEAD box helicase family, DEAH subfamily, DDX15/PRP43 sub-subfamily
Tissue Specificity
Ubiquitous.
Database Links

KEGG: mmu:13204

STRING: 10090.ENSMUSP00000031061

UniGene: Mm.993

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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