Diaph2 Antibody

1. mDia induces circumferential actin filaments around the edge of the synaptic cleft, which contract the presynaptic terminals in a ROCK-dependent manner. PMID: 27880913
2. These results imply that RhoD activated by FGF signaling forms cytoneme-like protrusions through activation of mDia3C, which induces actin filament formation PMID: 23034183
3. study examined how mDia functions in axon guidance in vivo and in vitro; findings show mDia plays multiple roles in the proper formation of the neural network PMID: 23890216
4. actin cytoskeleton regulated by Rho-mDia pathway is critical for the integrity of the adherens junctions and the polarity of neuroepithelial cells PMID: 21980468
5. Cdc42, and its effector, mDia3, regulate microtubule attachment to kinetochores PMID: 15085137
6. These results indicate that RhoA-dependent signaling through mDia1/2 and the MRTFs is important for SMC-specific gene expression in smooth muscle cells. PMID: 17170370
7. analysis of interactions between mDia isoforms 1, 2, and 3 and RhoA, Rac1, and Cdc42 PMID: 18829452

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STRING: 10090.ENSMUSP00000039334

UniGene: Mm.10763