Diedel Antibody

Code CSB-PA796973XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Diedel Polyclonal antibody
Uniprot No.
Target Names
Diedel
Alternative Names
Diedel antibody; die antibody; CG11501Protein Diedel antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Diedel protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Cytokine which promotes survival following infection by Sindbis virus by suppressing the immune deficiency pathway. Following infection by the enteropathogenic bacteria E.carotovora limits intestinal stem cells proliferation. When secreted from muscle or adipose tissue, can attenuate age-related intestinal tissue degeneration by inhibiting apoptosis.
Gene References into Functions
  1. die mutant flies have shortened lifespan and succumb more rapidly than controls when infected with Sindbis virus. PMID: 26739560
  2. Diedel, a marker of the Drosophila antimicrobial/antiviral response, is a member of a small family of proteins present in drosophilids, aphids and DNA viruses infecting lepidopterans PMID: 22442689
Subcellular Location
Secreted.
Protein Families
Diedel family
Tissue Specificity
Detected in hemolymph (at protein level). Also expressed in the fat body and is probably synthesized in the fat body and secreted into the hemolymph.
Database Links

KEGG: dme:Dmel_CG11501

UniGene: Dm.6307

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