dmsD Antibody

Code CSB-PA300896XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) dmsD Polyclonal antibody
Uniprot No.
Target Names
dmsD
Alternative Names
dmsD antibody; ynfI antibody; b1591 antibody; JW5262Tat proofreading chaperone DmsD antibody; DMSO reductase maturation protein antibody; Twin-arginine leader-binding protein DmsD antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) dmsD protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.
Gene References into Functions
  1. utilized the in vitro protein-protein interaction technique of an affinity pull down assay, as well as protein thermal stability measurement via differential scanning fluorimetry to investigate the interaction of guanosine nucleotides with DmsD PMID: 26299930
  2. Data suggest that a portion of the hydrophobic region of the DmsA (dimethyl sulfoxide reductase, subunit A) leader peptide determines the specificity of binding and may produce helical properties upon binding to DmsD. PMID: 24093457
  3. Results illustrate the positions of important DmsD residues involved in binding the DmsA leader peptide and identify a "hot pocket" of residues important for leader binding on the structure of DmsD. PMID: 18247574
  4. DmsD protein is required for reduction of selenate. PMID: 19415239
Subcellular Location
Cell inner membrane; Peripheral membrane protein. Cytoplasm. Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions.
Protein Families
TorD/DmsD family, DmsD subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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