Csp Antibody

Code CSB-PA311815XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Csp Polyclonal antibody
Uniprot No.
Target Names
Csp
Alternative Names
Csp antibody; CG6395DnaJ homolog subfamily C member 5 homolog antibody; Cysteine string protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Csp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
May have an important role in presynaptic function.
Gene References into Functions
  1. This review summarizes studies that elucidate the neuroprotective role of Drosophila CSP, which is critical for maintaining neurotransmitter release and preventing neurodegeneration. PMID: 20583963
  2. these data suggest that CSP promotes synaptic growth and evoked neurotransmitter release by mechanistically independent signaling pathways PMID: 17068777
  3. study found dHIP14 to be an essential maternal effect gene required for photoreceptor synaptic transmission and for proper in vivo expression of the palmitoylated presynaptic proteins SNAP-25 and cysteine string protein PMID: 18032660
  4. Our data indicate that HIP14 controls neurotransmitter release by regulating the trafficking of CSP to synapses. PMID: 18158335
Subcellular Location
Membrane; Lipid-anchor.
Tissue Specificity
Expressed in wide range of synaptic terminals: embryonic nervous system, larval neuromuscular junctions, adult visual system (neuropil of optic ganglia and terminal of R1-8 photoreceptors) and thoracic neuromuscular junctions. Also expressed in non-neuron
Database Links

KEGG: dme:Dmel_CG6395

STRING: 7227.FBpp0078146

UniGene: Dm.5140

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