gpp Antibody

Code CSB-PA811587XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) gpp Polyclonal antibody
Uniprot No.
Target Names
gpp
Alternative Names
gpp antibody; CG10272Histone-lysine N-methyltransferase antibody; H3 lysine-79 specific antibody; EC 2.1.1.360 antibody; DOT1-like protein antibody; dDOT1L antibody; Histone H3-K79 methyltransferase antibody; H3-K79-HMTase antibody; Protein grappa antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) gpp protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Required for Polycomb Group (PcG) and trithorax Group (trxG) maintenance of expression. Also involved in telomeric silencing but do not in centric heterochromatin. Probably participates in pairing sensitivity.
Gene References into Functions
  1. gpp is required for normal lifespan and stress resistance, and its overexpression increases stress resistance in Drosophila, without obvious induction of representative anti-oxidant genes. PMID: 19348653
Subcellular Location
Nucleus.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, DOT1 family
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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