DNApol-delta Antibody

Code CSB-PA018303XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) DNApol-delta Polyclonal antibody
Uniprot No.
Target Names
DNApol-delta
Alternative Names
DNApol-delta antibody; DNApolD1 antibody; PolD antibody; CG5949DNA polymerase delta catalytic subunit antibody; EC 2.7.7.7 antibody; 3'-5' exodeoxyribonuclease antibody; EC 3.1.11.- antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) DNApol-delta protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles. Likely to require the presence of accessory proteins Pol31 and Pol32 for full activity.
Subcellular Location
Nucleus. Nucleus, nucleoplasm.
Protein Families
DNA polymerase type-B family
Tissue Specificity
Expressed in ovaries (at the protein level). Expressed in embryos (at the protein level).
Database Links

KEGG: dme:Dmel_CG5949

STRING: 7227.FBpp0075277

UniGene: Dm.2838

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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