POL32 Antibody

1. Rev3 role in Pol32 regulation in the course of mutagenesis PMID: 24819597
2. A rad3/XPD mutation causes TFIIH retention at DNA damage and reduces gap filling. This rad3/XPD mutation causes replication fork breakage and double strand breakes rescued by Rad51- or Pol32-dependent recombination. PMID: 20227372
3. Strains deficient in Pol32 show little bypass of the T-T (6-4) photoadduct or the abasic sites. PMID: 15520252
4. Deletion of PIF1 suppresses the lethality of a DNA2-null mutant. Methylmethane sulfonate sensitivity and temperature sensitivity of the pif1delta dna2delta strain can be suppressed by further deletion of a subunit of pol delta, POL32. PMID: 16537895
5. Pol32, dispensable for replication and for gene conversion, is uniquely required for break-induced replication PMID: 17671506
6. Unlike Polzeta, inactivation of Pol32 does not result in decreased spontaneous mutagenesis, nor does it limit genome instability in the absence of the error-free postreplication repair pathway. PMID: 17681555
7. deletion of POL32, which encodes a third, nonessential subunit of polymerase delta, significantly reduced the efficiency of break-induced replication PMID: 18689895
8. The Pol32 subunit of the major replicative polymerase Poldelta is required for all Segmental duplications(SD) formation, demonstrating that SDs result from untimely DNA synthesis rather than from unequal crossing-over. PMID: 18773114
9. Results suggest that longer telomeres provide a more proficient substrate for a novel telomere maintenance mechanism that does not rely on telomerase, RAD52, or POL32. PMID: 19380905
10. Translocations rely on homologous recombination (HR) proteins, such as DNA repair enzymes, as well as on the break-induced replication-specific protein Pol32 and on Srs2. PMID: 19651902

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KEGG: sce:YJR043C

STRING: 4932.YJR043C