dps Antibody

Code CSB-PA690764XA01FPY
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Product Details

Full Product Name
Rabbit anti-Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) dps Polyclonal antibody
Uniprot No.
Target Names
dps
Alternative Names
dps antibody; dpsA antibody; Synpcc7942_2171DNA protection during starvation protein antibody; EC 1.16.-.- antibody; Nutrient stress-induced DNA-binding protein antibody
Raised in
Rabbit
Species Reactivity
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Immunogen
Recombinant Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2) dps protein
Immunogen Species
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. Soluble dps might function in iron homeostasis under high iron concentration, while the dps-DNA complex might associate with the protection of DNA from oxidative stress at low iron concentration. Has a weak catalase activity in vitro.
Subcellular Location
Cytoplasm. Note=The dps-DNA complex is found in the cytoplasm whereas a soluble dps is localized preferentially to the thylakoid membrane and is also found in the cell envelope.
Protein Families
Dps family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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