Dop2R Antibody

1. By means of genetic mosaicism, we identified widespread dopaminergic modulation within the olfactory circuit that suggests nonredundant and reiterating functions of D2R in support of ARM. Our results oppose ARM to its concomitant memory phases that localize to mushroom bodies and propose a decentralized organization of consolidated ARM. PMID: 27466338
2. The results suggest that fruit flies are an excellent model system to provide some answers to previously unexplainable observations regarding the compromised dopaminergic nervous system and the related therapeutic agents. PMID: 23286280
3. Our study also showed that rescue of dopaminergic (DA) neurodegeneration by Drosophila DD2R activation was mediated through suppression of action potentials in DA neurons. PMID: 23452092
4. It is concluded that the change in the number of DD2Rs in corpus allatum or their activation decreases the fitness of Drosophila. PMID: 22946336
5. mediates, at least in part, the inhibiting effect of dopamine on juvenile hormone synthesis PMID: 22206888
6. role of DD2R in the regulation of juvenile hormone metabolism PMID: 21928133
7. Alkaline phosphatase activity was increased in flies with reduced DD2R expression vs. corresponding controls. PMID: 20303975
8. Data show that activation of D2-like dopamine receptors inhibits juvenile hormone degradation in female Drosophila. PMID: 20665150
9. Molecular characterization and identification of multiple alternatively spliced variants PMID: 12391323
10. Locomotor activity is regulated by D2-like receptors in Drosophila PMID: 17443795

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KEGG: dme:Dmel_CG33517

STRING: 7227.FBpp0099564