DRP2B Antibody

Code CSB-PA881776XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DRP2B Polyclonal antibody
Uniprot No.
Target Names
DRP2B
Alternative Names
DRP2B antibody; ADL3 antibody; CF1 antibody; At1g59610 antibody; T30E16.17Dynamin-2B antibody; EC 3.6.5.5 antibody; Dynamin-like protein 3 antibody; Dynamin-related protein 2B antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana DRP2B protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Putative microtubule-associated force-producing protein, able to bind and hydrolyze GTP. Collaboratively with DRP1A, participates in clathrin-coated vesicle formation during endocytosis. With DRP1A and PIP5K3, required for the precise coordination of polar ARAC3/ROP6 and ARAC4/ROP2 placement and subsequent root hair positioning during planar polarity formation in root hair-forming cells.
Gene References into Functions
  1. It was found that all tested variants of AVR3a suppress defense responses triggered by flg22 and reduce internalization of activated FLS2. Moreover, AVR3a associates with the Dynamin-Related Protein 2 (DRP2), a plant GTPase implicated in receptor-mediated endocytosis. [DRP2B] PMID: 26348328
  2. this study adds DRP2B to the relatively short list of known vesicular trafficking proteins with roles in flg22-signaling and PTI in plants. PMID: 25521759
  3. Arabidopsis dynamin-related proteins, DRP1A and DRP2B, from two different families, participate in membrane remodeling at a similar place in the cell plate. [DRP2B] PMID: 18612642
Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasmic vesicle, clathrin-coated vesicle. Cell membrane.
Protein Families
TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
Tissue Specificity
Ubiquitous. Preferentially expressed in siliques.
Database Links

KEGG: ath:AT1G59610

STRING: 3702.AT1G59610.1

UniGene: At.23927

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