DTB1A Antibody

Datasheet
Code CSB-PA767244XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q7ZWE6
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) DTB1A protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Dysbindin-A (Biogenesis of lysosome-related organelles complex 1 subunit 8-A) (BLOC-1 subunit 8-A) (Dystrobrevin-binding protein 1-A) dtnbp1a bloc1s8 dtnbp1 zgc:56462
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names dtnbp1a
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neurite outgrowth (By similarity).
Subcellular Location Cytoplasm, Cytoplasmic vesicle membrane, Peripheral membrane protein, Cytoplasmic side, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Peripheral membrane protein, Cytoplasmic side, Endosome membrane, Peripheral membrane protein, Cytoplasmic side, Melanosome membrane, Peripheral membrane protein, Cytoplasmic side, Nucleus, Cell junction, synapse, postsynaptic cell membrane, postsynaptic density, Endoplasmic reticulum
Protein Families Dysbindin family
Database Links

KEGG: dre:394109

STRING: 7955.ENSDARP00000071887

UniGene: Dr.80474

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