dtpA Antibody

Code CSB-PA303527XA01ENV
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) dtpA Polyclonal antibody
Uniprot No.
Target Names
dtpA
Alternative Names
dtpA antibody; tppB antibody; ydgR antibody; b1634 antibody; JW1626Dipeptide and tripeptide permease A antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli (strain K12)
Immunogen
Recombinant Escherichia coli (strain K12) dtpA protein
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Proton-dependent permease that transports di- and tripeptides as well as structurally related peptidomimetics such as aminocephalosporins into the cell. Has a clear preference for dipeptides and tripeptides composed of L-amino acids, and discriminates dipeptides on the basis of the position of charges within the substrate.
Gene References into Functions
  1. The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells PMID: 29150447
  2. findings show YdgR can transport 5 drugs. cCells not overexpressing YdgR were also able to transport these drugs in a proton-dependent oligopeptide transporter-like manner; orthologues of YdgR are found in several species in the gut microbiome; findings could have implications for further understanding the interaction of gut microbes and orally administered drugs PMID: 28214542
  3. DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli PMID: 18485005
Subcellular Location
Cell inner membrane; Multi-pass membrane protein.
Protein Families
PTR2/POT transporter (TC 2.A.17) family, DtpA subfamily
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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