bli-3 Antibody

1. Here, the authors identified the Caenorhabditis elegans orthologue of mammalian mediator of ErbB2-driven cell motility, MEMO-1, as a protein that inhibits BLI-3/NADPH oxidase. PMID: 28085666
2. proline catabolism governs reactive oxygen species (ROS) homeostasis and subsequent activation of SKN-1, a critical transcription factor regulating xenobiotic stress response and pathogen defense. Intriguingly, proline catabolism-mediated activation of SKN-1 requires cell-membrane dual-oxidase Ce-Duox1/BLI-3, highlighting the importance of interaction between mitochondrial and cell-membrane components in host defense. PMID: 27974198
3. BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for the toxic pleiotropic effects of excess iodide. PMID: 25480962
4. We demonstrated that TSP-15, BLI-3, and DOXA-1 form complexes in vitro and in vivo. Cell-fusion-based analysis suggested that association with TSP-15 at the cell surface is crucial for BLI-3 activation to release H(2)O(2). PMID: 23028364
5. ROS generation by Ce-Duox1/BLI-3 activates a protective SKN-1 response via p38 MAPK signaling. PMID: 22216003
6. study of mutations of the DUOX1 truncated peroxidase domain to investigate possible role of the distal tyrosyl residue in heme binding; result argues that the DUOX peroxidase domain is primarily responsible for tyrosine cross-linking PMID: 20947510
7. Extracellular dopamine potentiates kanganese-induced oxidative stress, lifespan reduction, and neurodegeneration in a BLI-3-dependent manner. PMID: 20865164
8. Yeast mutants sod1Delta and yap1Delta fail to cause disease except in bli-3 worms which carry a mutation in a dual oxidase gene. PMID: 19502579

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KEGG: cel:CELE_F56C11.1

STRING: 6239.F56C11.1

UniGene: Cel.31857