DUSP14 Antibody

Code CSB-PA007243ZA01HU
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DUSP14 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
Dual specificity phosphatase 14 antibody; Dual specificity protein phosphatase 14 antibody; DUS14_HUMAN antibody; DUSP 14 antibody; DUSP14 antibody; DUSP14 protein antibody; MAP kinase phosphatase 6 antibody; Mitogen activated protein kinase phosphatase 6 antibody; Mitogen-activated protein kinase phosphatase 6 antibody; MKP 1 like protein tyrosine phosphatase antibody; MKP 6 antibody; MKP L antibody; MKP-1-like protein tyrosine phosphatase antibody; MKP-6 antibody; MKP-L antibody; MKP1 like protein tyrosine phosphatase antibody; MKP6 antibody; MKPL antibody
Raised in
Species Reactivity
Homo sapiens
Recombinant Homo sapiens DUSP14 protein
Immunogen Species
Homo sapiens (Human)
Purification Method
Protein A/G
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases.
Gene References into Functions
  1. Hepatocyte DUSP14 is required for maintaining hepatic metabolic homeostasis and for suppressing inflammation, a novel function that relies on constraining TAK1 hyperactivation PMID: 29077210
  2. The AA genotype was associated with protection against active TB. Among disease-free individuals, T-helper type-1 related genes, IFNGR2 and STAT1 mRNA levels significantly increased as the number of A alleles of rs1051838 increased. PMID: 26938665
  3. levels significantly decreased in failing hearts PMID: 26891723
  4. these findings reveal a novel mechanism by which TRAF2 mediates Lys63-linked ubiquitination of DUSP14, leading to DUSP14 activation in T cells PMID: 26521044
  5. findings suggest that DUSP14 negatively regulates TNF- or IL-1-induced NF-kappaB activation by dephosphorylating TAK1 at Thr-187 PMID: 23229544
  6. DUSP14 may be a susceptibility gene for pulmonary tuberculosis. PMID: 22233810
  7. The overproduction, purification and crystal structure at 1.88 A resolution of human dual-specificity phosphatase 14, DUSP14 (MKP6), are reported. PMID: 19770498
  8. Activation of ATM by radiation down-regulates phospho-ERK1/2 and its downstream signaling via increased expression of mitogen-activated protein kinase phosphatase MKP-1. PMID: 17178844
  9. The binding of Lipomannan to TLR2 triggers MAPK activation, followed by an up-regulation of MKP-1 expression, which in turn may act as a negative regulator of MAPK activation. PMID: 18201568

Show More

Hide All

Protein Families
Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
Database Links

HGNC: 17007

OMIM: 606618

KEGG: hsa:11072

STRING: 9606.ENSP00000377910

UniGene: Hs.91448

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join Us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2023 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1