DUT Antibody

Code CSB-PA865972XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) DUT Polyclonal antibody
Uniprot No.
Target Names
DUT
Alternative Names
DUT antibody; DUT1 antibody; At3g46940 antibody; T6H20.30Deoxyuridine 5'-triphosphate nucleotidohydrolase antibody; dUTPase antibody; EC 3.6.1.23 antibody; dUTP pyrophosphatase antibody; dUTP-pyrophosphatase-like 1 antibody; AtDUT1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana DUT protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP, preventing uracil incorporation into DNA.
Gene References into Functions
  1. Data indicate that the structure of the Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) showed three active sites, each with a different set of ligand interactions between the amino acids and water molecules. PMID: 26666293
  2. dUTPase function is conserved between E. coli (Escherichia coli), yeast (Saccharomyces cerevisiae) and Arabidopsis (Arabidopsis thaliana) and that it is essential in Arabidopsis as in both micro-organisms. PMID: 21541310
Protein Families
DUTPase family
Database Links

KEGG: ath:AT3G46940

STRING: 3702.AT3G46940.1

UniGene: At.48742

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