dyf-5 Antibody

Code CSB-PA164210XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans dyf-5 Polyclonal antibody
Uniprot No.
Target Names
dyf-5
Alternative Names
dyf-5 antibody; M04C9.5Serine/threonine-protein kinase dyf-5 antibody; EC 2.7.11.1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans dyf-5 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos.
Gene References into Functions
  1. DYF-5 plays a role in the undocking of kinesin II from intraflagellar transport (IFT) particles and in the docking of OSM-3 onto IFT particles. PMID: 17420466
Subcellular Location
Perikaryon. Cell projection, dendrite. Cell projection, axon. Cell projection, cilium.
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, RCK subfamily
Tissue Specificity
Expressed in head neurons including amphid and labial sensory neurons and 3 pairs of neurons in the tail including phasmid sensory neurons. In male, expressed in the tail including the sensory rays and the spicule.
Database Links

KEGG: cel:CELE_M04C9.5

STRING: 6239.M04C9.5b

UniGene: Cel.27349

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