Dlc90F Antibody

Code CSB-PA821987XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Dlc90F Polyclonal antibody
Uniprot No.
Target Names
Dlc90F
Alternative Names
Dlc90F antibody; Tctex antibody; CG12363Dynein light chain Tctex-type antibody; TCTEX-1 protein homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Dlc90F protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Required for spermatid differentiation. Is not required for polarized transport in rhabdomere development and appears to be a non-essential component of the cytoplasmic dynein complex.
Gene References into Functions
  1. Dynein light chain 1 is required for protein clearance by autophagy that is associated with autophagic cell death and neurodegeneration. PMID: 20080745
  2. Dlc90F is required for the localization of cytoplasmic dynein and is not essential for early development or in the adult organism. PMID: 15090621
  3. x-ray crystallographic analysis of dynein light chain TcTex-1 structure PMID: 15701632
Subcellular Location
Cytoplasm, cytoskeleton.
Protein Families
Dynein light chain Tctex-type family
Database Links

KEGG: dme:Dmel_CG12363

STRING: 7227.FBpp0082996

UniGene: Dm.2045

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