DYT1 Antibody

1. Early onset torsion dystonia (DYT1) patient fibroblasts with heterozygous DYT1 mutant alleles showed decreased herpes simplex virus 1 plaque formation as compared to controls. PMID: 29396398
2. DYT1 dystonia is a network disorder, with crucial nodes in sensory-motor integration of posterior parietal structures. PMID: 27453152
3. The results of this study suggested that motor impairments in DYT1 KI animals only exhibit when the sensory stimuli are strongly altered during performance. PMID: 27769743
4. Data said that the normal spatio-temporal subcellular localization of DYT1 is important for DYT1 function and/or that the BIF domains from different bHLH members might be functionally distinct. PMID: 27113773
5. Here the authors demonstrate abnormal risk taking in DYT1 dystonia patients, which is correlated with disease severity, thereby supporting striatal plasticity in shaping choice behavior in humans. PMID: 27249418
6. we show the behavioral and molecular consequences of stressing the endoplasmic reticulum in DYT1 mice by increasing the amount of misfolded proteins PMID: 27707963
7. DYT1 forms complexes with bHLH010, bHLH089 and bHLH091 subsequently affecting the correct expression of many DYT1 target genes. PMID: 26216374
8. DYT1 positively regulates genes for lipid metabolism, cell-wall modification and secondary metabolism that are important for pollen development. PMID: 22775442
9. DYT1 encodes a putative bHLH transcription factor and is a component of a genetic network that controls anther development and function. [DYT1] PMID: 16831835

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KEGG: ath:AT4G21330

STRING: 3702.AT4G21330.1

UniGene: At.54456