eas Antibody

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Code	CSB-PA345758XA01DLU
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Target Background

Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) eas Polyclonal antibody

Uniprot No.

P54352

Target Names

eas

Alternative Names

eas antibody; CG3525 antibody; Ethanolamine kinase antibody; EK antibody; EC 2.7.1.82 antibody; Protein easily shocked antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) eas protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

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Target Background

Function

Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.

Gene References into Functions

eas has a critical role in phosphatidylethanolamine synthesis and dendrite morphogenesis in sensory neurons. PMID: 29069593
induction of eas(+) in adult mutant flies rescues them from seizure sensitivity despite previously known developmental defects in brain PMID: 23682034
Tissue-specific and developmental effects of the easily shocked mutation on ethanolamine kinase activity and phospholipid composition in Drosophila melanogaster. PMID: 11758729
Data demonstrate that ethanolamine (Etn) kinase activity is required in mushroom body neuroblasts to allow a rapid rate of cell division at metamorphosis, linking Etn kinase activity with mitotic progression. PMID: 15766757

Subcellular Location

Cytoplasm.

Protein Families

Choline/ethanolamine kinase family

Database Links

KEGG: dme:Dmel_CG3525

STRING: 7227.FBpp0073990

UniGene: Dm.6855

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