ECM38 Antibody

Code CSB-PA210300XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ECM38 Polyclonal antibody
Uniprot No.
Target Names
ECM38
Alternative Names
ECM38 antibody; CIS2 antibody; YLR299WGlutathione hydrolase proenzyme antibody; EC 3.4.19.13 antibody; CIK1 suppressor protein 2 antibody; Extracellular mutant protein 38 antibody; Gamma-glutamyltransferase antibody; EC 2.3.2.2 antibody; Gamma-glutamyltranspeptidase antibody; Gamma-GT) [Cleaved into: Glutathione hydrolase heavy chain; Glutathione hydrolase light chain] antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ECM38 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the transfer of the gamma-glutamyl moiety of glutathione (GSH) and other gamma-glutamyl compounds to amino acids and peptides. Major GSH-degrading enzyme, catalyzing the hydrolytic release of L-glutamate from GSH. Plays a role in the turnover of the vacuolar GSH, serving as an alternative nitrogen source during nitrogen starvation.
Gene References into Functions
  1. Data suggest that metabolism of electrophilic xenobiotics in the yeasts H. polymorpha and S. cerevisiae occurs through a gamma-glutamyltranspeptidase-dependent mercapturic acid pathway similar to that known for mammalian cells. PMID: 16857395
Subcellular Location
Vacuole membrane; Single-pass type II membrane protein.
Protein Families
Gamma-glutamyltransferase family
Database Links

KEGG: sce:YLR299W

STRING: 4932.YLR299W

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