Ge-1 Antibody

Code CSB-PA894238XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Ge-1 Polyclonal antibody
Uniprot No.
Target Names
Ge-1
Alternative Names
Ge-1 antibody; CG6181Enhancer of mRNA-decapping protein 4 homolog antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Ge-1 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
In the process of mRNA degradation, seems to play a role in mRNA decapping. Required for silencing a subset of endogenous miRNA targets.
Gene References into Functions
  1. we identified a deletion in the protein-coding region of a gene called Ge-1 in flies that are highly resistant to a naturally occurring virus called sigma virus PMID: 26799957
  2. Findings suggest an important role of dGe-1 in optimization of the osk mRNA localization process required for patterning the Drosophila embryo. PMID: 21655181
  3. The three-dimensional crystal structure of the most conserved region of the Drosophila melanogaster Ge-1 C-terminal domain was determined. PMID: 18755833
Subcellular Location
Cytoplasm, P-body.
Protein Families
WD repeat EDC4 family
Database Links

KEGG: dme:Dmel_CG6181

STRING: 7227.FBpp0079818

UniGene: Dm.12439

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