EFNA5 Antibody

Datasheet
Code CSB-PA228524XA01DIL
Product Type Polyclonal Antibody
Uniprot No. P79728
Delivery Make-to-order
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) EFNA5 protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Ephrin-A5b (AL-1) (EPH-related receptor tyrosine kinase ligand 7) (LERK-7) (ZfEPHL4) efna5b al1 efna5 eplg7 lerk7
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Protocols ELISA Protocol
Gene Names efna5b
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the epha3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor epha2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation (By similarity). Controls axon growth and may be involved in the creation of the retino-tectal map.
Subcellular Location Cell membrane, Lipid-anchor, GPI-anchor
Protein Families Ephrin family
Tissue Specificity Widespread expression in the embryo.
Database Links

KEGG: dre:30223

STRING: 7955.ENSDARP00000092347

UniGene: Dr.19377

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