EFR Antibody

Code CSB-PA495669XA01DOA
Size Enquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) EFR Polyclonal antibody
Uniprot No.
Target Names
EFR
Alternative Names
EFR antibody; At5g20480 antibody; F7C8.70LRR receptor-like serine/threonine-protein kinase EFR antibody; EC 2.7.11.1 antibody; Elongation factor Tu receptor antibody; EF-Tu receptor antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana EFR protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of elongation factor Tu (EF-Tu), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs); phosphorylates BIK1 upon elicitation to regulate immune responses such as defense hormone expression (e.g. jasmonic acid (JA) and salicylic acid (SA)). Reduces transformation by Rhizobium radiobacter probably by inducing plant defense during the interaction. Binding to the effector AvrPto1 from P.syringae blocks the downstream plant immune response while interaction with hopD2 decreases the phosphorylation level of EFR upon elf18 treatment. Specific endoplasmic reticulum quality control components (ERD2B, CRT3, UGGT and STT3A) are required for the biogenesis of EFR.
Gene References into Functions
  1. transgenic rice plants (Oryza sativa L. ssp. japonica cv. Zhonghua 17) and cell cultures with constitutive expression of AtEFR were developed to investigate whether AtEFR senses EF-Tu and thus enhances bacterial resistance in the monocot plants. PMID: 25358295
  2. When challenged with the cereal bacterial pathogen Pseudomonas syringae pv. oryzae, transgenic EFR wheat lines had reduced lesion size and bacterial multiplication. PMID: 25760815
  3. OST3/6 deficiency affects the biogenesis of EFR, resulting in the impairment of innate immunity. OST3/6 plays an important role for abiotic stress tolerance and for the functionality of the endoglucanase KOR1 essential for cellulose biosynthesis. PMID: 23493405
  4. A knockout mutant showed reduced downy mildew infection, but susceptibility was fully restored through complementation of the mutation, suggesting that the (malectin like)LRR-RLK contributes to disease. PMID: 21711359
  5. The effects of protein domain mutations on the binding properties of EFR and FLS2 are reported. PMID: 21063169
  6. The ligand-induced heteromerization of EFR and FLS2 with BAK1 is independent of kinase activity in planta. PMID: 21593986
  7. Activation of FLS2 and EFR by bacterial peptide elicitors led to calcium-associated plasma membrane anion channel opening. PMID: 20113440
  8. EFR(N143Q) lacking a single conserved N-glycosylation site from the EFR ectodomain accumulated to reduced levels and lost the ability to bind its ligand and to mediate elf18-elicited oxidative burst. PMID: 20007973
  9. These results show that the plasma membrane pattern-recognition receptor EFR requires the endoplasmic reticulum complex SDF2-ERdj3B-BiP for its proper accumulation. PMID: 19763086

Show More

Hide All

Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Database Links

KEGG: ath:AT5G20480

STRING: 3702.AT5G20480.1

UniGene: At.31176

CUSABIO guaranteed quality
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1