egl-27 Antibody

Code CSB-PA136903XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans egl-27 Polyclonal antibody
Uniprot No.
Target Names
egl-27
Alternative Names
egl-27 antibody; C04A2.3Egg-laying defective protein 27 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans egl-27 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor which promotes stress survival and delays aging. Required for cell cycle progression and development of the mesodermal and endodermal embryonic lineages. Required for normal T-cell polarity, for correct migration of QL neuroblast descendants and other cells, for embryonic patterning and for the embryonic expression of hlh-8. Also required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development.
Gene References into Functions
  1. the GATA transcription factor EGL-27 co-regulates DAF-16 target genes in response to DNA damage and together with DAF-16 promotes developmental growth. PMID: 25419847
  2. These results identify egl-27 as a novel factor that links stress and aging pathways. PMID: 23271974
Subcellular Location
Nucleus.
Tissue Specificity
Expression detected in anterior intestine and head region.
Database Links

KEGG: cel:CELE_C04A2.3

STRING: 6239.C04A2.3a

UniGene: Cel.17167

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