ELP2 Antibody

Code CSB-PA007626XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ELP2 Polyclonal antibody
Uniprot No.
Target Names
ELP2
Alternative Names
ELP2 antibody; GNS1 antibody; At1g49540 antibody; F13F21.2 antibody; F14J22.24Elongator complex protein 2 antibody; AtELP2 antibody; Elongator component 2 antibody; Protein GREEN NPR1 SEEDLING ON SA MEDIUM 1 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana ELP2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. Promotes organs development by modulating cell division rate. Prevents abscisic acid (ABA) signaling leading to stomatal closure and seedling growth inhibition. Involved in oxidative stress signaling. Prevents anthocyanins accumulation. Accelerator of defense gene induction required for rapid defense gene induction, and for the establishment of both basal and effector-triggered immunity (ETI), in a NPR1-independent manner, but is not required for systemic acquired resistance (SAR) establishment.
Gene References into Functions
  1. ELP2 positively contributes to resistance to the necrotrophic fungal pathogens Botrytis cinerea and Alternaria brassicicola. PMID: 26216741
  2. The elp2 mutant had accelerated differentiation of root stem cells and cell division was more active in its quiescent centre (QC); the key transcription factors responsible for maintaining root stem cell and QC identity were all strongly down-regulated. PMID: 25998905
  3. ELP2 plays an evolutionarily conserved role in DNA demethylation/methylation in plants and likely functions as an epigenetic regulator of plant immune responses. PMID: 23435660
  4. AtELP2 is an accelerator of defense gene induction, which functions largely independently of NPR1 in establishing plant immunity. PMID: 20807211
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
WD repeat ELP2 family
Tissue Specificity
Expressed in leaves, stems, roots, flowers, siliques and guard cells.
Database Links

KEGG: ath:AT1G49540

STRING: 3702.AT1G49540.2

UniGene: At.49962

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