nfo Antibody

Datasheet

Code	CSB-PA363838XA01ENV
Size	Enquire
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Escherichia coli (strain K12) nfo Polyclonal antibody

Uniprot No.

P0A6C1

Target Names

nfo

Alternative Names

nfo antibody; b2159 antibody; JW2146Endonuclease 4 antibody; EC 3.1.21.2 antibody; Endodeoxyribonuclease IV antibody; Endonuclease IV antibody

Raised in

Rabbit

Species Reactivity

Escherichia coli (strain K12)

Immunogen

A synthesized peptide derived from Escherichia coli (strain K12) nfo protein

Immunogen Species

Escherichia coli (strain K12)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, Dot blot (guaranteed specific to the immunizing peptide)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

①. 100ug * KLH-conjugated peptide paired with 100ug * BSA-conjugated peptide (positive control);
②. 1ml*pre-immune serum (used as negative control) for free;
③. Rabbit polyclonal antibodies purified by Antigen Affinity;

Quality Guarantee

1. CUSABIO guarantees the antibody purity > 95% confirmed by SDS-PAGE.
2. CUSABIO guarantees the antibody titer > 1: 64,000 confirmed by ELISA.
3. CUSABIO guarantees to offer Peptide-specific Dot blot.
4. CUSABIO guarantees 100% risk-free: No qualified antibody, no charge.

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.

Gene References into Functions

Novel Nfo substrates alpha-2'-deoxyadenosine and alpha-thymidine play an important role in counteracting oxidative DNA base damage. PMID: 15568813
analysis of the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV PMID: 17242363
Biochemical, mutational & crystallographic characterization reveal a 3-metal ion mechanism for damage binding and incision; DNA-free and DNA-substrate complex structures capture substrate stabilization by Arg37 and show a distorted Zn3 ligand arrangement. PMID: 18408731

Protein Families

AP endonuclease 2 family

Database Links

KEGG: ecj:JW2146

STRING: 316385.ECDH10B_2316

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

SWISS-PROT: When and How to Use It Protein Acetylation: An Important Post-translational Modification in Eukaryotic Cells Neuronal Markers and Neurodegenerative Diseases What Are Histones: Unraveling Their Critical Roles in Disease Pathogenesis Does Antibody-dependent Enhancement Occur in SARS-CoV-2 Infection? Decoding the Biological Complexity of Endometrial Cancer: Essential Insights for Researchers Information You Must Know about KCNN4 Streptococcus pneumoniae, a Primary Cause of Pneumonia The True Face of Tumor Suppressor Gene p53 Two Types of Macrophages: M1 and M2 Macrophages EGFR and Its Application in Cancer Therapy The Overview of One Category of Important Cell Receptors: Receptor Tyrosine Kinases Cross-reactivity of Antibody: Beneficial or Harmful? GCGR: A Regulator of Energy Balance Holds a Potential in Treatment Diabetes TNFR1: Elucidating Dual Mechanisms and Evolving as a Precision Therapeutic Target Approaches to Determinate Protein Concentration Lysosomal Enzymes and Lysosomal Storage Disorders (LSDs) Cellular Senescence and Its Markers How to Choose? Polyclonal, Monoclonal, or Recombinant Antibody? DNA Damage and Repair Chemokine Receptor CCR4: the Key Role of CCR4+Treg Cells in Cancer Immunotherapy Streamlining Antibody Internalization Assessment with DT3C: Accelerating ADC Candidate Selection Recombinant Monkeypox Virus Proteins - Accelerate Monkeypox Research CD93, A Rising Star in Anti-Tumor Therapy With the High Potential in Cancer Immunotherapy, CD40 Is Triggering Attention ERBB3/HER3: a New Target for Tumor Therapy, a Driver Gene of Multi-Tumors How Do You Get Exosomes? A Hands‑On Guide to Isolation, Enrichment, and Quality Control Cell Differentiation Determines the Fate of Cells Twice Halted in One Year! Is Akeso's CD73 Monoclonal Antibody in Jeopardy Again? Is PD-1's Golden Partner Still Worth It? Exploring Biological Landscape of Cervical Cancer: A Comprehensive Overview for Researchers What Are the Best Methods for Protein Purification? A Practical Guide TFR1 (TFRC): a Stimulator of Fe Transport Affects Anemia, Neurodegenerative Disorders and Cancers! Categories over 10000! --Rare diseases that are no longer Protein Phosphorylation: The Dynamic Language of Cellular Regulation Tuberculosis--A Resurgent A Review of WFDC8 Antibody Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies? Microglial Markers: Insights into Microglial Activation and Function How to Inquire and Utilize the Signal Pathway on KEGG The Overview of Fc Receptors- Classification, Related Signaling Pathways and Application Effects of FSHR on Fertility and Tumors MYL9: a New Member of Myosin Motors, a Key Driver of Cancer Cell Dynamic Regulation? ZG16B: A New Tumor Biomarker Offers Important Insights for Drug Development in Pancreatic Cancer! New Mechanism, NRP1 Enhances the Ability of SARS-CoV-2 Infection CEACAM8: a Member of CEA Family, Emerging as a Vital Player in Gynaecological or Gastrointestinal Cancer Research! Biological Activity of Proteins Stem Cell-What a Miraculous Resource in Human Body IL-6-Do You Really Know That? Nanobody, what a Powerful Novel Antibody! What Do You Need to Know Before Researching Human Metapneumovirus? DKK1: a Well-Characterized Wnt Inhibitor, a Multifunctional Regulator in Multiple Cancers! One World, One Hope——What Can We Do about AIDS? The Application of IHC in Pathological Diagnosis Toll-like Receptors--The Eye of Innate Immunity A Comprehensive Exploration into Amyotrophic Lateral Sclerosis CD46, A Complement Regulator The Meaning of Irregular Antibody Screening CD47, A New Target for Tumor Immune A "trembling" Parkinson's Disease What Is Immune Checkpoint Therapy? What Are Immune Checkpoint Pathways? CD20 Monoclonal Antibodies Drugs: There is an Explosion of New mAbs Against CD20! The Overview of Coagulation Understanding of Serum Albumin VSIG4: a Prominent B7 Family Costimulatory Molecule or Complement Receptor in Cancers and Inflammatory Diseases! Monoclonal Antibody Drugs Overview SLC39A6/ZIP6: a Key Member of Zinc Transporters, a Novel Targeting Antigen of ADC! What You Have To Know about Lung Cancer TMEFF2: a Tumor-Specific Methylated Biomarker, a Novel Target in Multiple Cancers Protein Kinases Overview: Definition, Types, Function, Activation Mechanism, etc. The Recently Emerged New Swine Influenza Virus -- G4 EA-H1N1 Tools You Need For Fundamental Research What Powerful Model Organism Databases Protein Tyrosine Kinases: Anti-tumor Targets to be Explored Urgently TCGA Database- A Good Partner of Researchers GIPR: the Crucial Regulator of Glucose and Lipid Metabolism in Diabetes and Obesity! What a Powerful Artifact of DNA Compression - Histone How Does Histone Modification Affect Gene Expression? Histone modification and Cancer About Thyroid Tumor: Essential Information for Researchers What A Paradoxical TNF Signaling Pathway-Based on Different Receptors What Essential Biological Knowledge is Needed for Hepatocellular Carcinoma Research? These Tumor Databases You Have To Know CD146, A Powerful Tumor Marker ELISA vs. Multiplex Immunoassays: Why ELISA Remains the Gold Standard among Immunoassays GPCR Drugs Discovery Accelerating Diverse Antibody Discovery: The Power of Single B Cell Platforms ACE2, The Hottest Target of SARS-CoV-2 Invasion Epitope Tags Overview Tetraspanin CD81: a Key Receptor for Hepatitis C Virus (HCV), an Established Exosome Marker, a Promising Target for Antiviral or Antitumor Research! Does TNF Superfamily Inhibit Cancer or Promote Its Development? TMPRSS2, an Activator for SARS-CoV-2 Invasion CD Antigens - From Leucocytes Surface Markers to Diagnostic Markers for Cancer How to express a protein with bioactivity? How to Choose the Right ELISA Kit for Your Research? Norwalk Virus Analysis of Factors Influencing ELISA Detection ALPG: a Germ Cell-Associated Alkaline Phosphatase (ALP), a Highly Specific Cell Surface Antigen in Cancers! Serotransferrin/TF: a Major Transferrin in Plasma, a Novel TF-Modified Nanoparticle for Tumor-Targeting Research! Do You Really Know Neurons and Glia Cells in Nerve System? Apoptosis mediated by endoplasmic reticulum Nanoparticle platform Get An Overview of His-Tag EphA3-A Regulator of Cell Adhesion and Migration The Memory thief - Alzheimer's disease The Overview of Growth Factor Tumor Necrosis Factor (TNF) The Overview of Interferon The Oncogene HER2: a New Target for Drug-Resistant Tumors Cell Cycle Markers in Focus: From Basic Research to Biomarker Discovery in Oncology The Overview of Interleukin The Overview of Organelles The Overview of Autophagy The Four Types of ELISA: Principles, Innovations, and Evolving Applications How to Choose an Antibody for Scientific Research? Production of Recombinant Protein Phage Display: From Antibody Discovery to Therapeutic Breakthroughs Crosstalk Between Apoptosis and Autophagy: Molecular Mechanisms and Therapeutic Strategies in Cancer The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic Targets The overview of Wnt signaling pathway The overview of TGF-β signaling pathway The Encyclopedia of Common Virus The "Plaque Cleaner" in Blood Vessels Has Arrived! CD25+ Regulatory T Cells Transform into CAR-Tregs with Amazing Results What Should You Know about Exosomes? GUCY2C: a Novel Target in Tumor Immunotherapy, Specially in Colorectal Cancer CAR T Therapy! SSTR2: A Prominent Target in SSTR Family, Offers a More Precise Therapy in Neuroendocrine Tumors (NET) MAGEA4: a Member of the Melanoma-Associated Antigen (MAGE) Family, a Popular Target for Tumor-Specific Immune Research! In Vivo vs. In Vitro: Choosing the Right Experimental Model for Your Research Dipeptidase 3 (DPEP3): an Emerging Member of the DPEP Family, a Potential Therapeutic Target in Male Fertility or Tumor Research! Exploring Protein-Protein Interactions: A Comprehensive Guide to Understanding and Utilizing It CT83/KK-LC-1: a Promising Therapeutic Target of CTAs Family, Currently in Clinical Research for Breast, Lung, Gastric Cancers, and Beyond! What Are the Best Antibody Purification Methods for Your Research Needs? What is Myc Tag: Definition, Function, Applications & Comparison with Other Epitope Tags What Is Protein Characterization: Definition, Examples, Methods, and Techniques Nectin-4: a Key Target in the IgSF Family, Boosting Clinical Drug Research in Various Tumors! Verified vs. Unverified Recombinant Proteins: Making the Right Choice for Your Research How to Choose Monoclonal Antibody Technology? A Definitive Guide What Bacterial Antigens Are Used in Vaccines? What Is Compartment Modelling in Pharmacokinetics? ACVR2A and ACVR2B as Key Targets for Muscle Growth, Weight Loss, PHA in Drug Research！ TNFSF15/TL1A: The Rise of the Next Billion-Dollar Target as Pharma Giants Stake Their Claims How to Choose An Appropriate Isotype Control Antibody? CD79A and CD79B: Key Targets in B Cell Signaling Pathways and Therapeutic Potential How AI is Reshaping Biological Research? A Comprehensive Guide to Tools and Practical Strategies How to Choose the Right Recombinant Protein for Your Experimental Model? How the Tumor Microenvironment Fuels Cancer's Deadly Evolution Decoding Recombinant Protein Expression: Strategic Solutions & Practical Insights Pioneering CAR-T Cell Therapy: Advancing Personalized Cancer Treatment How Do CTLA-4 Inhibitors Work? A Complete Guide for Early-Career Researchers CCL17: A Chemokine with Multiple Biological Functions PTH1R: Key Therapeutic Target in Bone & Metabolic Health Nicotinic Acetylcholine Receptor α1 Subunit (CHRNA1): Structure, Functional Mechanisms, and Disease-Related Research Progress The Metabolic Achilles' Heel of Cancer Stem Cells: New Mechanism of LGR5 Reveals Metformin's Anticancer Potential Metabolic Hub, Reprogramming Disease: SLC3A2 – From Amino Acid Transport Mechanism to Emerging Therapeutic Target Targeting EphA2: An Emerging Focus in Combating Tumor Drug Resistance and Metastasis Macrophage Migration Inhibitory Factor (MIF): A Pleiotropic Target Linking Inflammation and Cancer Western Blotting: Principles, Step-by-Step Workflow, and Troubleshooting Guide GPR20: From "Orphan" to a Promising Novel Target for Overcoming Drug-Resistant GIST BTLA: An Emerging Target in Immunotherapy – New Insights into Cancer and Autoimmune Diseases PDGFRA: A Hub in Cellular Signaling and a Therapeutic Target The Multifaceted World of ADAM9: Beyond Proteolytic Function CRLF2 (TSLPR): A Key Target Linking Type 2 Inflammation to Hematologic Malignancies ACVR1C/ALK7: An Emerging Target in Metabolic Diseases and Cancer Therapy Research-Grade Biosimilar Antibodies: Practical Tools for Mechanism, Assay, and PK Studies From "Physical Barrier" to "Signaling Hub": How Mucin MUC1 Drives Tumor Progression Spanning Eight Major Cancers: Why Has Transmembrane Mucin MUC13 Become a New Focus in Precision Tumor Therapy? ASGR1: From Hepatic Clearance Receptor to Novel Target for Metabolic and Cardiovascular Disease Therapy B2M/β2-Microglobulin: From Antigen Presentation Core to Key Target for Immunotherapy and Disease Prediction BDNF/Brain-Derived Neurotrophic Factor: From Neuroplasticity Regulation to Core Target for Neuropsychiatric Disease Therapy CD28: Molecular Mechanism and Therapeutic Progress of the Core Co-Stimulatory Receptor in T Cells CCN2 (CTGF) Target: Core Molecule of Fibrosis and Tumor Stroma Regulation | Disease Treatment Research Progress BTN3A1 (CD277) Target: γδ T Cell Immune Recognition Mechanism and Cancer Immunotherapy Research Progress CD33 (Siglec-3) Signaling Pathways and Disease Mechanisms: Roles in Acute Myeloid Leukemia, Alzheimer’s Disease and Immune Regulation CD40LG: A Key Molecule in Immune Regulation, Disease Associations and Therapeutic Progress Fibroblast Growth Factor 2 (FGF2): Molecular Mechanisms, Signaling Pathways, Disease Associations and Therapeutic Advances The CD200/CD200R Signaling Axis: A Critical “Brake” in Maintaining Immune Homeostasis Beyond PD-1/CTLA-4! The Emerging Immune Checkpoint CD160 is Transforming the Landscape of Tumor Immunotherapy Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

nfo Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background