ERC6L Antibody

Datasheet
Code CSB-PA007775XA01DIL
Product Type Polyclonal Antibody
Uniprot No. A2BGR3
Delivery Make-to-order
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) ERC6L protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias DNA excision repair protein ERCC-6-like (EC 3.6.4.12) (ATP-dependent helicase ERCC6-like) ercc6l si:ch211-278b8.3
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Protocols ELISA Protocol
Gene Names ercc6l
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Functions as ATP-dependent DNA translocase. Can promote Holliday junction branch migration (in vitro).
Subcellular Location Chromosome, centromere, Chromosome, centromere, kinetochore, Chromosome
Protein Families SNF2/RAD54 helicase family
Database Links

KEGG: dre:100005291

STRING: 7955.ENSDARP00000012447

UniGene: Dr.38615

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