sup35 Antibody

Code CSB-PA526733XA01SXV
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Product Details

Full Product Name
Rabbit anti-Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) sup35 Polyclonal antibody
Uniprot No.
Target Names
sup35
Alternative Names
sup35 antibody; SPCC584.04Eukaryotic peptide chain release factor GTP-binding subunit antibody; ERF-3 antibody; ERF3 antibody; ERF2 antibody; Polypeptide release factor 3 antibody; Translation release factor 3 antibody
Raised in
Rabbit
Species Reactivity
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Immunogen
Recombinant Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) sup35 protein
Immunogen Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in translation termination. Stimulates the activity of ERF1. Binds guanine nucleotides.
Gene References into Functions
  1. we localized another suppressor gene to the sup35 locus and we determined that the mechanism of suppression involves an amino acid substitution in a GTP elongation factor Tu domain of the ubiquitous eukaryotic translation release factor 3 (eRF3). PMID: 25519804
  2. Hsp104 disaggregase is unable to propagate the [PSI] prion PMID: 19759825
  3. eRF1's M domain contacts eRF3's GTPase domain PMID: 19417105
Subcellular Location
Cytoplasm.
Protein Families
TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, ERF3 subfamily
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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