ets-4 Antibody

Code CSB-PA799570XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans ets-4 Polyclonal antibody
Uniprot No.
Target Names
ets-4
Alternative Names
ets-4 antibody; F22A3.1 antibody; Transcription factor ets-4 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans ets-4 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Transcription factor which binds to 5'-GGAA/T-3' DNA consensus sequences. Both positively and negatively regulates the expression of target genes. Plays a role in the regulation of adult lifespan, which may in part be through modulation of daf-16 activity. Regulates the expression of genes such as svh-2 in response to axon injury and in addition, may function downstream of the cAMP signaling pathway to promote axon regeneration. Regulates the expression of lipid metabolism genes and may also control the expression of the RNA-binding protein rege-1 which too has been implicated in the control of fat accumulation.
Gene References into Functions
  1. The transcription factor ETS-4, an ortholog of vertebrate SPDEF, is a longevity determinant. PMID: 20862312
Subcellular Location
Nucleus.
Protein Families
ETS family
Tissue Specificity
Expressed in cells of the anterior and posterior bulbs of the pharynx, seam cells, a few unidentified cells of the vulva, the hypodermis, several unidentified neurons, labial socket cells of the head and rectal cells.
Database Links

KEGG: cel:CELE_F22A3.1

STRING: 6239.F22A3.1b

UniGene: Cel.38733

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