eva-1 Antibody

Code CSB-PA196097XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans eva-1 Polyclonal antibody
Uniprot No.
Target Names
eva-1
Alternative Names
eva-1 antibody; F32A7.3Protein eva-1 antibody; Enhancer of ventral-axon guidance defects of unc-40 mutants antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans eva-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Acts as a receptor for slt-1. Required for the guidance of the AVM pioneer axon to the ventral nerve cord. Acts as a unc-40 coreceptor to enhance the sensitivity of unc-40 to the madd-4 midline guidance cue to guide muscle arm extensions (muscle arms) and AVM mechanosensory axons towards the dorsoventral midline.
Gene References into Functions
  1. EVA-1 identified as a transmembrane receptor for SLT-1; EVA-1 acts cell-autonomously for SLT-1/Slit-dependent axon migration functions of SAX-3/Robo, colocalizes with SAX-3 on cells & provides cell specificity to activation of SAX-3 signaling by SLT-1 PMID: 17901337
Subcellular Location
Cell membrane; Single-pass membrane protein.
Protein Families
EVA1 family
Database Links

KEGG: cel:CELE_F32A7.3

STRING: 6239.F32A7.3a

UniGene: Cel.18817

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