EXO70 Antibody

Code CSB-PA324836XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) EXO70 Polyclonal antibody
Uniprot No.
Target Names
EXO70
Alternative Names
EXO70 antibody; YJL085W antibody; J0932Exocyst complex component EXO70 antibody; Exocyst complex protein of 70 kDa antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) EXO70 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Plays a role in the assembly of the exocyst.
Gene References into Functions
  1. Data indicate structural details of the interaction of exocyst complex Sec3p and Exo70p with lipid bilayers containing phosphatidylinositol (4,5)-bisphosphate (PIP2) by molecular dynamics simulations. PMID: 25838123
  2. The structure of the exocyst subunit Exo70p is presented. PMID: 16249794
  3. structure provides a first view of the Exo70 protein family and provides a framework to study the molecular function of this exocyst component PMID: 16359701
  4. Exo70p functions primarily at early stages of the cell cycle in Bgl2p vesicle secretion, which is critical for polarized cell growth. PMID: 17339375
  5. Exo70 mediates the assembly of the exocyst complex at the plasma membrane, which is a crucial step in the tethering of post-Golgi secretory vesicles for exocytosis. PMID: 17717527
  6. The results suggest that either Exo70p or Sec3p must associate with the plasma membrane for the exocyst to function as a vesicle tether. PMID: 18946089

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Subcellular Location
Cytoplasmic vesicle, secretory vesicle. Bud. Bud neck.
Protein Families
EXO70 family
Database Links

KEGG: sce:YJL085W

STRING: 4932.YJL085W

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