Sec6 Antibody

Code CSB-PA896058XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Sec6 Polyclonal antibody
Uniprot No.
Target Names
Sec6
Alternative Names
Sec6 antibody; CG5341Exocyst complex component 3 antibody; Exocyst complex component Sec6 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Sec6 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Gene References into Functions
  1. Sec6 is an exocyst complex component believed to bind secretory vesicles to plasma membrane sites. Sec6 mutations cause cell death and disrupt plasma membrane growth. In developing photoreceptor cells (PRCs) Sec6 shows accumulation at adherens junctions PMID: 15897260
  2. The Drosophila exocyst component sec6 in epithelial cells results in DE-Cad accumulation in an enlarged Rab11 recycling endosomal compartment and inhibits DE-Cad delivery to the membrane. PMID: 16224820
Protein Families
SEC6 family
Database Links

KEGG: dme:Dmel_CG5341

STRING: 7227.FBpp0085888

UniGene: Dm.4250

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