rib-1 Antibody

Code CSB-PA515314XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans rib-1 Polyclonal antibody
Uniprot No.
Target Names
rib-1
Alternative Names
rib-1 antibody; F12F6.3 antibody; Exostosin-1 homolog antibody; Multiple exostoses homolog 1 antibody; Related to mammalian RIB protein 1 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans rib-1 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Required for the biosynthesis of heparan sulfate by positively regulating N-acetylglucosamine transferase II (GlcNAcT-II) and glucuronyl transferase II (GlcAT-II) activities of glycosyltransferase rib-2. Probably not directly involved in chondroitin sulfate biosynthesis but negatively regulates chondroitin sulfate levels. Maternally required for normal ventral epidermal enclosure and for embryo elongation during the early stages of embryonic development. In addition, involved in the elongation of the pharyngeal isthmus and in the organization of the actin cytoskeleton in the pharyngeal muscles during the later stages embryonic development. In adults, regulates egg-laying and the normal morphogenesis of the vulva. Also involved in the directed migration of hermaphrodite-specific neurons.
Subcellular Location
Endoplasmic reticulum. Golgi apparatus.
Protein Families
Glycosyltransferase 47 family
Database Links

KEGG: cel:CELE_F12F6.3

STRING: 6239.F12F6.3.2

UniGene: Cel.18208

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