Ecel1 Antibody

Code CSB-PA878117ZA01MO
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Ecel1 Polyclonal antibody
Uniprot No.
Target Names
Ecel1
Alternative Names
Ecel1 antibody; Dine antibody; XceEndothelin-converting enzyme-like 1 antibody; EC 3.4.24.- antibody; Damage-induced neuronal endopeptidase antibody; Xce protein antibody
Raised in
Rabbit
Species Reactivity
Mus musculus
Immunogen
Recombinant Mus musculus Ecel1 protein
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
Gene References into Functions
  1. This study demonstrated that the ECEL1/DINE G607S and C760R mutations both lead to motor innervation defects as primary causes in ECEL1-mutated congenital contracture disorders. PMID: 29132416
  2. DINE is expressed in cranial and spinal motor neurons both embryonically and after CNS injury PMID: 27656015
  3. DINE enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury. PMID: 28569783
  4. Using two different DINE mutant mice, study found that DINE functional disruption leads to impaired axonal arborization of motor nerves in limb muscles. PMID: 26951213
  5. The data of this study suggested that DINE is a crucial molecule in distal axonal arborization into muscle to establish neuromuscular junctions. PMID: 20484637

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Subcellular Location
Membrane; Single-pass type II membrane protein.
Protein Families
Peptidase M13 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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