FAB1A Antibody

Code CSB-PA447025XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FAB1A Polyclonal antibody
Uniprot No.
Target Names
FAB1A
Alternative Names
FAB1A antibody; At4g33240 antibody; F4I10.1701-phosphatidylinositol-3-phosphate 5-kinase FAB1A antibody; Phosphatidylinositol 3-phosphate 5-kinase antibody; EC 2.7.1.150 antibody; FYVE finger-containing phosphoinositide kinase antibody; PIKfyve antibody; Phosphatidylinositol 3-phosphate 5-kinase type III antibody; PIPkin-III antibody; Type III PIP kinase antibody; Protein FORMS APLOID AND BINUCLEATE CELLS 1A antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana FAB1A protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters.
Gene References into Functions
  1. overexpression of FAB1A-GFP reassembles SNX2b-mRFP on the endosomal membrane despite the absence of SNX1. PMID: 26515455
  2. Activity of FAB1 proteins is essential for the development of viable pollen. [FAB1A] PMID: 19846542
Subcellular Location
Endosome membrane; Peripheral membrane protein.
Tissue Specificity
Ubiquitous with highest expression levels in pollen, seed, and senescent leaves.
Database Links

KEGG: ath:AT4G33240

STRING: 3702.AT4G33240.1

UniGene: At.28052

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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