Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FAB1B Polyclonal antibody

Uniprot No.

Q9LUM0

Target Names

FAB1B

Alternative Names

FAB1B antibody; At3g14270 antibody; MLN21.61-phosphatidylinositol-3-phosphate 5-kinase FAB1B antibody; Phosphatidylinositol 3-phosphate 5-kinase antibody; EC 2.7.1.150 antibody; FYVE finger-containing phosphoinositide kinase antibody; PIKfyve antibody; Phosphatidylinositol 3-phosphate 5-kinase type III antibody; PIPkin-III antibody; Type III PIP kinase antibody; Protein FORMS APLOID AND BINUCLEATE CELLS 1B antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana FAB1B protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Plays an important role in maintenance of endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification processes. Required for development of viable pollen. Might mediate recycling of auxin transporters.

Gene References into Functions

The function of the Arabidopsis genes encoding FAB1B and FAB1D, both highly expressed in pollen, were investigated. PMID: 24807078
Data indicate that single and double mutants of phosphatidylinositol 3-phosphate 5-kinases (PI3P5Ks) FAB1A, FAB1B, FAB1C and FAB1D exhibited slow stomatal closure upon ABA treatment. PMID: 23757398
Results suggest that impairment of the function of Arabidopsis FAB1A/B might cause a defect in the membrane recycling capabilities of the auxin transporters and inhibit proper auxin transport into the cells in Arabidopsis. PMID: 21412048
Imbalanced expression of FAB1A/B impairs endomembrane homeostasis including endocytosis, vacuole formation, and vacuolar acidification. PMID: 21173023
Activity of FAB1 proteins is essential for the development of viable pollen. [FAB1B] PMID: 19846542

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Subcellular Location

Endosome membrane; Peripheral membrane protein.

Tissue Specificity

Ubiquitous with highest expression levels in the root hair zone, pollen, and stamens.

Database Links

KEGG: ath:AT3G14270

STRING: 3702.AT3G14270.1

UniGene: At.23226

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FAB1B Antibody

Product Details

Customer Reviews and Q&A

Target Background